Bisnucleophiles
WebMay 27, 2024 · An oxidative [3+3] annulation of atropaldehyde acetals with various 1,3-bisnucleophiles was developed using either N-bromosuccinimide or copper(II) bromide as oxidizing reagent and Brønsted or Lewis acids as catalyst.The [3+3] annulations can be considered mechanistically as oxidizing reagent-induced acid-acid-catalyzed domino … Web1).18–22 The action of bisnucleophiles, such as diamines, on compounds 1a , b was mechanistically expected to result in a one-step spiro-to-spiro ring transformation of the chroma-
Bisnucleophiles
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WebOct 26, 2024 · Herein, we report the efficient and facile use of 3-carboxamide oxindoles as 1,3-C,N bisnucleophiles in the reactions with α,β-unsaturated trifluoromethyl ketones, … WebDec 28, 2024 · A new method for the synthesis of α-trifluoromethylated tertiary alcohols bearing coumarins is described. The reaction of 3-(trifluoroacetyl)coumarin and pyrrole provided the target compounds with high yields under catalyst-free, mild conditions. The crystal structure of compound 3fa was investigated by X-ray diffraction analysis. The …
WebPPh 3 ‑Catalyzed [3 + 2] Spiroannulation of 1C,3N‑Bisnucleophiles Derived from Secondary β‑Ketoamides with δ‑Acetoxy Allenoate: A Route to Functionalized Spiro N‑Heterocyclic Derivatives Author links open overlay panel Jiaojiao Xing † , Yu Lei † , Yu-Ning Gao † , Min Shi †, ‡, § Web职称：教授、博士生导师. 部门：化学学院. 联系方式：. Tel: 86-512-65880307. Fax: 86-512-65880307. Email:[email protected]. 课题组网站. Research Interests: Applied synthetic organic chemistry: Organic reactions of isocyanides; Multicomponent reactions or tandem reaction synthesis of biologically active heterocyclic ...
WebMar 1, 2008 · Reaction of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidine 1 with 1,3- and 1,4-bisnucleophiles has been investigated; obtainment of new polycyclic heterocyclic derivatives is reported.
WebPPh 3 ‑Catalyzed [3 + 2] Spiroannulation of 1C,3N‑Bisnucleophiles Derived from Secondary β‑Ketoamides with δ‑Acetoxy Allenoate: A Route to Functionalized Spiro …
WebApr 1, 2024 · β-Ketoesters as Mono- or Bisnucleophiles: A Concise Enantioselective Total Synthesis of (−)-Englerin A and B. M. Sc. Lei Guo, M. Sc. Lei Guo. Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany. Search for more papers by this author. therapeutic intervention words listWeb1,4-Bisnucleophiles have often been used for constructing heterocycles with a seven-membered ring, such as o-phenylenediamine, 2-aminobenzenethiol and 2-mercaptoa- signs of forgetfulness vs alzheimer\u0027sWebSep 29, 2024 · A copper-catalyzed asymmetric propargylic [3+3] cycloaddition with 1H-pyrazol-5(4H)-ones as C,O-bisnucleophiles through the desilylation-activated strategy has been developed.With the catalysis of Cu(OAc) 2 ·H 2 O in combination with a chiral tridentate P,N,N-ligand, the reaction displayed a broad substrate scope, and thus … therapeutic interventions list documentationWebJun 17, 2024 · β-Ketoesters as Mono- or Bisnucleophiles: A Concise Enantioselective Total Synthesis of (-)-Englerin A and B. A short enantioselective total synthesis of … signs of food spoilage pdfWebOver the past few decades, transition metals have found wide applications in the development of selective oxidative transformations mediated by molecular oxygen. Due to the benign nature of molecular oxygen as an oxidant and an increasing awareness of green chemistry practice, tremendous progress has been made towards the development of Cu … signs of foot cancerWebApr 1, 2024 · β‐Ketoesters as Mono‐ or Bisnucleophiles: A Concise Enantioselective Total Synthesis of (−)‐Englerin A and B - Guo - 2024 - Angewandte Chemie International … therapeutic ionsWebchloride (12), readily reacted with bisnucleophiles such as primary amines or activated methylene compounds to form a five-membered heterocyclic ring annulated onto the benzene moiety in a one-pot reaction, we decided to apply this approach to synthesize isoindolin-1-ones 3 (phthalimidines) as well. signs of foundation cracking